mario kart should work fine. what emulator are you running? most people get best results using the non-libretro version of mupen64plus + the gles64 plugin. you can choose it if you hit ‘x’ key when loading the rom.
the libretro version of mupen64plus is out of date as far as i can tell, or at least set up weirdly. i’m not sure why it’s still the default in retropie – it’s awful!
n64 is definitely a little ropey, but there’s a lot of games that work nearly perfectly. mario kart and f-zero are great in 4 player mode, even (some sound issues) :)